Here is a list of selected publications from the BRAIN team and collaborators, highlighting the use of preclinical imaging & corroborative methods at KCL:


Crum, W.R., Sawiak, S.J., Chege, W., Cooper, J.D., Williams, S.C.R., Vernon, A.C., 2017.
Evolution of structural abnormalities in the rat brain following in utero exposure to maternal immune activation: A longitudinal in vivo MRI study.
Brain Behavior and Immunity 1–10.

Westphal, R., Simmons, C., Mesquita, M.B., Wood, T.C., Williams, S.C.R., Vernon, A.C., Cash, D., 2017.
Characterization of the resting-state brain network topology in the 6-hydroxydopamine rat model of Parkinson’s disease.
PLoS ONE 12, e0172394–18.


Cash, D., Easton, A.C., Mesquita, M., Beech, J.S., Williams, S., Lloyd, A., Irving, A.J., Cramer, S.C., 2016. GSK249320,
A Monoclonal Antibody Against the Axon Outgrowth Inhibition Molecule Myelin-Associated Glycoprotein, Improves Outcome of Rodents with Experimental Stroke.
Journal of Neurology and Experimental Neuroscience 2, 28–33.

Duricki, D.A., Hutson, T.H., Kathe, C., Soleman, S., Gonzalez-Carter, D., Petruska, J.C., Shine, H.D., Chen, Q., Wood, T.C., Bernanos, M., Cash, D., Williams, S.C.R., Gage, F.H., Moon, L.D.F., 2016.
Delayed intramuscular human neurotrophin-3 improves recovery in adult and elderly rats after stroke.
Brain 139, 259–275.

Petrinovic, M.M., Hankov, G., Schroeter, A., Bruns, A., Rudin, M., Kienlin, von, M., Künnecke, B., Mueggler, T., 2016.
A novel anesthesia regime enables neurofunctional studies and imaging genetics across mouse strains.
Sci. Rep. 6, 1–12.

Tomimatsu, Y., Cash, D., Suzuki, M., Suzuki, K., Bernanos, M., Simmons, C., Williams, S.C.R., Kimura, H., 2016.
TAK-063, a phosphodiesterase 10A inhibitor, modulates neuronal activity in various brain regions in phMRI and EEG studies with and without ketamine challenge.
Neuroscience 339, 180–190.

Walker, T., Michaelides, C., Ekonomou, A., Geraki, K., Parkes, H.G., Suessmilch, M., Herlihy, A.H., Crum, W.R., So, P.-W., 2016.
Dissociation between iron accumulation and ferritin upregulation in the aged substantia nigra: attenuation by dietary restriction.
Aging (Albany NY) 8, 2488–2508.

Westphal, R., Sumiyoshi, A., Simmons, C., Mesquita, M., Wood, T.C., Williams, S.C.R., Vernon, A.C., Cash, D., 2016.
Characterization of gray matter atrophy following 6-hydroxydopamine lesion of the nigrostriatal system.
Neuroscience 334, 166–179. doi:10.1016/j.neuroscience.2016.07.046

Wood, T.C., Simmons, C., Hurley, S.A., Vernon, A.C., Torres, J., Dell’Acqua, F., Williams, S.C.R., Cash, D., 2016.
Whole-brain ex-vivo quantitative MRI of the cuprizone mouse model.
PeerJ 4, e2632.


Turkheimer, F.E., Leech, R., Expert, P., Lord, L.-D., Vernon, A.C., 2015.
The brain’s code and its canonical computational motifs. From sensory cortex to the default mode network: A multi-scale model of brain function in health and disease.
Neuroscience & Biobehavioral Reviews 55, 1–12.

Vernon, A.C., So, P.-W., Lythgoe, D.J., Chege, W., Cooper, J.D., Williams, S.C.R., Kapur, S., 2015.
Longitudinal in vivo maturational changes of metabolites in the prefrontal cortex of rats exposed to polyinosinic–polycytidylic acid in utero.
European Neuropsychopharmacology 25, 2210–2220.


Finlay, C.J., Duty, S., Vernon, A.C., 2014.
Brain morphometry and the neurobiology of levodopa-induced dyskinesias: current knowledge and future potential for translational pre-clinical neuroimaging studies.
Front Neurol 5, 95.

Guidine, P.A.M., Cash, D., Drumond, L.E., de Souza e Rezende, G.H., Massensini, A.R., Williams, S.C.R., Moraes-Santos, T., Moraes, M.F.D., Mesquita, M.B.S., 2014.
Brainstem structures are primarily affected in an experimental model of severe scorpion envenomation.
Toxicological Sciences 137, 147–157.

Vernon, A.C., Crum, W.R., Lerch, J.P., Chege, W., Natesan, S., Modo, M., Cooper, J.D., Williams, S.C.R., Kapur, S., 2014.
Reduced Cortical Volume and Elevated Astrocyte Density in Rats Chronically Treated With Antipsychotic Drugs—Linking Magnetic Resonance Imaging Findings to Cellular Pathology.
Biological Psychiatry 75, 982–990.

2013, and earlier

Crum, W.R., Modo, M., Vernon, A.C., Barker, G.J., Williams, S.C.R., 2013.
Registration of challenging pre-clinical brain images.
Journal of Neuroscience Methods 216, 62–77.

Mesquita, M.B.S., Medeiros, D. de C., Cota, V.R., Richardson, M.P., Williams, S., Moraes, M.F.D., 2011.
Distinct temporal patterns of electrical stimulation influence neural recruitment during PTZ infusion: an fMRI study.
Prog. Biophys. Mol. Biol. 105, 109–118.

Vernon, A.C., Johansson, S.M., Modo, M.M., 2010.
Non-invasive evaluation of nigrostriatal neuropathology in a proteasome inhibitor rodent model of Parkinson’s disease.
BMC Neurosci 11, 1.

Littlewood, C.L., Cash, D., Dixon, A.L., Dix, S.L., White, C.T., O’Neill, M.J., Tricklebank, M., Williams, S.C.R., 2006.
Using the BOLD MR signal to differentiate the stereoisomers of ketamine in the rat.
NeuroImage 32, 1733–1746.