by Admin | Feb 11, 2018 | Blogs & posts, Gallery
Thanks to our clinical MRS expert Dr David Lythgoe, with help of our own Dr Camilla Simmons, we now have a working protocol for magnetic resonance spectroscopy – yey! This is an example spectrum from a (tiny) 11.6um voxel of a mouse prefrontal cortex (see inset...
by Admin | Nov 30, 2017 | Blogs & posts, Gallery
High resolution (0.08mm voxels) of a fixed rat head that was pre-soaked in Gadolinium-contaning buffer for 1 week to increase signal to noise. Acquired using standard Bruker 3D T2W-RARE (Rapid Imaging with Refocused Echoes, aka Fast Spin Echo, FSE) in just over 2h. In...
by Admin | Nov 12, 2017 | Blogs & posts, Gallery
The three-dimension magnetization-prepared rapid gradient echo (MP-RAGE) sequence is one of the most popular sequences for high-resolution whole brain T1-weighted imaging in the clinic. Thanks to Eugene and Toby, we now have it working nicely in mouse brain as part of...
by Admin | Nov 9, 2017 | Blogs & posts, Gallery
At BRAIN centre we don’t just do MRI. With Nisha Singh and Marta Vicente-Rodriguez we recently optimised the methodology for in vivo preclinical PET imaging of PK11195 binding to mitochondrial translocator protein, TSPO (a putative neuroinflammation marker) and...
