T1W (MP-RAGE) MRI of the mouse brain

T1W (MP-RAGE) MRI of the mouse brain

The three-dimension magnetization-prepared rapid gradient echo (MP-RAGE) sequence is one of the most popular sequences for high-resolution whole brain T1-weighted imaging in the clinic. Thanks to Eugene and Toby, we now have it working nicely in mouse brain as part of...
TSPO PET & autoradiography

TSPO PET & autoradiography

At BRAIN centre we don’t just do MRI. With Nisha Singh and Marta Vicente-Rodriguez we recently optimised the methodology for in vivo preclinical PET imaging of PK11195 binding to mitochondrial translocator protein, TSPO (a putative neuroinflammation marker) and...